Unreasonable Impact Americas 2024

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Americas 2024

Our team at Unreasonable shares a sentiment with Barclays that solving the world’s toughest challenges is not only a moral imperative — it’s also an unprecedented financial opportunity. We further acknowledge that the greatness of what we ultimately achieve will be determined by the quality of the relationships we build. Towards this end, we are humbled that you are joining us for our 2024 Unreasonable Impact Americas gathering.

Launched in 2016, we co-created Unreasonable Impact with Barclays. Since its inception, our global partnership has focused on three regions: the UK & Europe, the Americas, and Asia Pacific. Today, we are actively supporting more than 330 ventures that are headquartered across 45 countries, have collectively raised more than $14 bn in financing, have mitigated over 111 million metric tons of CO2 equivalent from our atmosphere, and employ more than 31,000 people.

We are proud to now connect you with the entrepreneurs who have been selected for this year’s Americas program. These innovators are working to pull a more just and regenerative future into the present. The entrepreneurs you’ll be meeting have, as a cohort, already raised more than $1.8bn in financing and are operating in more than 10 countries. Together we have the privilege of supporting their efforts now and into the future. On behalf of Barclays and Unreasonable, I simply want to express my most sincere and humble thanks for being a part of their journey.

With gratitude,

This booklet provides a brief introduction to each of the ventures participating in the Unreasonable Impact program. For a comprehensive understanding of their work, please scan the QR code on each page to access the Unreasonable app.

The QR code will direct you to the Unreasonable app, where you can access detailed information about each venture’s mission, impact focus, notable achievements, operating territories, and more. You can also connect directly with the entrepreneurs through the app. The “Notes” section on each page is available for you to jot down your thoughts and questions as you learn more about these ventures throughout the program.

1doc3.com

Sector Healthcare

Founded in 2014

Financing to date

$6.3M

Employees 51-100

HQ Mexico City, Mexico

1DOC3 is a B2B Health and Wellness platform providing employees with instant access to telemedicine, including general physicians, psychologists, nutritionists, and veterinarians. The platform, operating in Mexico and Colombia, features AI to streamline consultations and offers health and wellness tracking tools. Serving 150,000 employees across 120 companies, 1DOC3 plans to expand its coverage to 1 million by 2026, further enhancing its primary care services.

Key Achievements

• Works with 120 companies , covering 150,000 employees and their families .

• Featured in Mark Zuckerberg’s keynote speech at the 2017 annual F8 conference

Aigen

Sector Agricultural Technology

Founded in 2020

Financing to date

$19M Employees 21-50

HQ Washington, USA

Aigen’s mission is to regenerate earth through robotics and AI, starting with agriculture. Aigen’s Element robots, which are self-sustaining, solarpowered, and autonomous, provide farmers with alternatives to herbicides for crop protection. Using AI, Aigen delivers high-resolution crop insights over greater temporal and spatial scales, helping improve farm management and fostering sustainable agriculture worldwide. By 2025, Aigen plans to expand its technology to cover multiple crops.

Key Achievements

• Raised $19M from investors, including NEA, ReGen, and Cleveland Ave.

• Sold out demand (pre-orders) for the next 2-3 years.

• Featured in Fast Company’s Most Innovative Companies in Agriculture for 2024.

Apis Cor

apis-cor.com

Apis Cor is revolutionizing construction with its proprietary 3D printing technology, capable of printing full-scale buildings. The company provides and rents 3D printers and special concrete blends to automate construction processes. Apis Cor uses innovative technology to scale up production, reduce environmental impact, and address global housing shortages.

Key Achievements

• Holds Guinness World Record for largest 3D-printed building.

• Received strategic investment from D.R.Horton and plan to work together on a multi-unit construction project in South Florida.

• Winner of NASA’s Centennial Challenge.

Attane Health

attane-health.com

Attane Health is a digital health platform designed to provide personalized, nutrition-specific care for Medicaid populations. The company offers nutrientdense food prescriptions, telehealth nutrition coaching, and actionable data insights to help improve health outcomes. By focusing on chronic health conditions, Attane Health is addressing food insecurity and health disparities through innovative, scalable solutions. The company aims to expand its reach and improve user experiences across its growing network of 57 countries.

Key Achievements

• Raised $4M , with investors including Bluestein Ventures, Builders Vision, KCRise Fund, Acumen America, and Beta Boom.

• Named a “2023 Company to Watch” by Startland News.

• Ranked the #1 Food and Nutrition Care platform by the Medicaid Innovation Collaborative’s Medicaid Consumer Panel.

Circ recycles the most abundant waste streams from the textile industry—polyester, cotton, and polycotton blends—into high-quality materials that can be reused by the textile supply chain. Circ is uniquely capable of breaking down polycotton blends, a known challenge for the industry. Through its patented process, Circ has developed the only inmarket solution to successfully separate polycotton blended textile waste and recover both cellulosic and synthetic fibers, enabling collaboration with brands like Zara, Target, Mara Hoffman, and Christian Siriano. Circ’s long-term goal is to scale this solution globally to address the most significant environmental challenges in the industry while delivering tremendous value for its customers and partners.

HQ Virginia, USA

Key Achievements

• Certified B Corporation

• Fast Company’s Most Innovative Companies (2024)

• The Earthshot Prize Finalist (2023)

Dispatch Goods

Dispatch Goods optimizes cold chain packaging through a circular logistics model —- think about bringing back the “milkman.” Companies work with Dispatch Goods to launch returnable cold chain packaging programs (ice packs, insulation, tote bags, boxes, etc) so that a consumer can set packaging out for returns, and it’s easily whisked away to be processed for reuse. By creating returnable packaging programs for businesses delivering perishable goods, and the vast amount of packaging needed to maintain temperature, including meal and grocery, prepped meals, and now pharma, Dispatch Goods creates a beloved user experience and reduces waste and cost for the brand.

Key Achievements

HQ California, USA

• Over 6M items replaced from the waste stream to date.

• Successfully launched profitable operations in two markets.

• 25,000 households regularly returning cold chain items.

planeterthos.com

HQ Ontario, CA

erthos® leverages AI and biomaterials to design sustainable alternatives to traditional plastics. The company’s proprietary platform, ZYA™, accelerates the creation of biomaterials that meet both performance and environmental standards. Operating across 20 countries, erthos® works with leading companies to reduce plastic dependency by developing scalable, eco-friendly materials. The company’s innovations aim to reshape industries, from fashion to food, by providing sustainable, high-quality materials for global markets.

Key Achievements

• Raised over $11M from investors like Horizons Ventures.

• Developed biomaterials for 20+ product categories, including personal care, food, home and fashion.

• Founders recognized globally, including Forbes 30 Under 30, Canadian Governor General’s Award, New York Weekly, etc.

Fit:Match

Founded

Fit:Match revolutionizes shopping with its patented 3D technology that matches consumers to clothing based on their unique body shape. Using advanced algorithms, the platform captures 3D data and compares it against a database of similar body profiles to recommend perfectly fitting clothes. With its data-driven approach, FIT is expanding into retail and biomedical sectors, enhancing customer experiences and driving innovation across industries.

Key Achievements

• Partnered with iconic brands in retail and fitness.

• Expanded technology applications into the biomedical market

Guidewheel

guidewheel.com

Sector Manufacturing Technology

Founded in 2017

Financing to date $21M Employees 21-50

HQ California, USA

Guidewheel provides real-time visibility and analytics for factory operations using non-intrusive sensors that monitor equipment’s electrical activity. By detecting patterns and anomalies, Guidewheel helps factories reduce downtime, optimize productivity, and enhance energy efficiency. With hundreds of customers worldwide, the company’s AI-powered platform enables manufacturers to achieve net-zero emissions and sustainable performance. Guidewheel’s mission is to scale AI-driven productivity improvements globally.

Key Achievements

• Working with hundreds of manufacturers globally across the US, Latin America, Europe, Asia, and Africa.

• Recognized as a Tech Pioneer by the World Economic Forum and highlighted at Davos 2024 .

• Raised from top investors , including Greycroft, Breakthrough Energy Ventures and BlackRock & Temasek’s Decarbonization Partners fund.

hyfe.tech

Hyfé is pioneering the bio-refining of food waste into alternative carbon sources, offering a circular solution to replace petroleum in producing chemicals, materials, and food. The company partners with food processors to upgrade waste streams into sustainable bioproducts. Backed by top food-tech investors and supported by the Department of Energy through the Chain Reaction Innovations grant program from Argonne National Laboratory, Hyfé is scaling its operations to contribute to a sustainable, waste-free future.

Key Achievements

• Developing scalable bio-refining technology to convert food waste into valuable products. Sector

• Raised $11M from climate and food-tech investors like MIT’s Engine Ventures and Synthesis Capital.

• Supported by the Department of Energy’s Chain Reaction Innovations grant.

LuxWall

LuxWall manufactures vacuum-insulated glass, significantly reducing energy consumption and emissions in commercial and residential buildings. By integrating its high-performance glass into existing buildings and new construction, LuxWall offers a transformative solution for energy efficiency. The company has scaled production in Michigan and is actively expanding operations in the U.S., Canada, and the U.K. LuxWall is committed to delivering high-impact glass solutions to accelerate the shift toward net-zero buildings.

Key Achievements

• Raised $46M in Series Seed and A from Breakthrough Energy, Prelude Ventures, 2150, Baruch Future Ventures, and Khosla Ventures.

HQ Michigan, USA

• Secured a $20M customer pipeline with over 50 unique customers. Sector

• Built a factory to produce vacuum-insulating glass with an R-18 insulation value.

Odyssey Energy Solutions

Odyssey Energy Solutions accelerates distributed renewable energy deployment in growth markets by connecting solar companies and financiers through its end-to-end technology platform. Odyssey’s platform streamlines the solar financing process from origination to asset management, making it easier for energy companies to access capital and build projects faster. Odyssey is accelerating the clean energy transition in emerging markets, enabling millions of people to access affordable, reliable, and clean energy.

Key Achievements

• Facilitating over $2B of capital committed to distributed energy projects in emerging markets.

• More than 2.5 million systems funded via the platform, impacting over 10 million lives .

• Raised $20M in funding from Union Square Ventures and others.

Prolific Machines

prolific-machines.com

Sector

Biotechnology

Founded in 2020

Financing to date

$88M

Employees 51-100

HQ California, USA

Prolific Machines is at the forefront of biotechnology, using light and AI to control cellular behavior to produce food, pharmaceuticals, and other innovations. By utilizing light as a control mechanism, Prolific enables unprecedented precision in cellular processes, unlocking new possibilities for bioproduct manufacturing. With a focus on scaling its platform to established manufacturers, Prolific aims to revolutionize cellular agriculture, drug discovery, and other biological manufacturing markets.

Key Achievements

• Raised $88M from investors like Breakthrough Energy Ventures, Mayfield & IndieBio, etc.

• Developed a next-generation antibody therapeutics platform with a grant from the Gates Foundation.

• Created the world’s first meatball grown with light .

TAE Technologies

tae.com

TAE Technologies is pioneering commercial fusion power development to deliver clean, safe, and abundant carbon-free electricity to the grid. TAE is the world’s leader in hydrogen-boron fusion – the most economical and environmentally friendly approach – to address the world’s growing energy needs. With more than 2,300 patents filed and multiple National Laboratory-scale fusion devices, TAE is poised to deliver transformational energy solutions capable of sustaining the planet for centuries. The company’s innovations extend to technologies in power management, energy storage, electric mobility, and life sciences.

Key Achievements

• Filed over 2,300 patents globally, with approximately 1,500 granted.

• Developed five generations of fusion energy devices , with two more in progress. Sector

• Raised more than $1.2 billion in private capital.

Wild Earth

Sector Food Technology

Founded in 2017

Financing to date $42M Employees 6 - 20

HQ North Carolina, USA

Wild Earth is a leader in plant-based pet food, creating cruelty-free, clean protein foods for dogs and cats. The company’s innovative products are designed to be healthier for pets while reducing the environmental impact of traditional meatbased pet foods. With over $45M in revenue and multiple product launches, Wild Earth is reshaping the pet food industry with a focus on sustainability, nutrition, and animal welfare.

Key Achievements

• Generated over $45M in revenue since its launch.

• Launched 15 new product SKUs into the market.

zordi.com

Sector Agricultural Technology

Founded in 2020

Financing to date

$20M

Employees 6 - 20

HQ Massachusetts, USA

Zordi is revolutionizing the food supply chain by combining traditional greenhouse architecture with AI-powered robotics to create an automated, scalable, and sustainable agricultural solution. The company’s technology reduces labor costs by 80% while increasing crop yields, offering an attractive economic profile for greenhouse operations. Currently focused on growing strawberries, Zordi plans to expand its platform to other fruiting crops as it scales its AI-driven robotic greenhouse solution.

Key Achievements

• Raised $20M , with lead investment from Khosla Ventures.

• Selling out high-quality strawberries in Manhattan, NY, NJ and beyond.

• Operating two pilot greenhouses with multiple robots in NY & NJ.

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